Mapping a Mutation
Activity 3: Slides 16–23.
Students learn about the genetic code, and how small substitutions within the code can lead to physical changes in individuals. Students use authentic data to uncover the single nucleotide polymorphism (SNP) responsible for long hair in dogs.
In the previous activity, students were introduced to the wide variety of characteristics found across breeds of dogs. They used information produced by modern genetics research to learn which breeds of dogs were most related and how genetics information is used commercially to help people figure the history and possible parentage of mixed breed dogs. These examples represent applications of genomics—a field that offers a new way of thinking about genes and heredity.
1. Introduce the topic of genes and genomes by presenting this slide.
- Tasha the boxer courtesy of the National Human Genome Research Institute. Public domain.
- Moreno, N. (2017) Complex Traits: Using Dogs as a Model for Modern Genetics. Baylor College of Medicine: Houston. ISBN: 978-1-994035-08-2.
- Help Me Understand Genetics. Genetics Home Reference. U.S. National Library of Medicine.
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