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Author(s): Nancy Moreno, PhD, Barbara Tharp, MS, Deanne Erdmann, MS, Sonia Rahmati Clayton, PhD, and James Denk, MA.

High-power Microscopes

Scientists use a variety of high-powered microscopes to study the surface and internal structure of a sample, and to measure the size of things too tiny to see with light microscopes. 

An electron microscope uses a beam of accelerated electrons as a source of illumination. A transmission electron microscope (TEM) can magnify objects or microbes up to 10,000,000x. Most light microscopes magnifies samples at up to 2,000x. A scanning electron microscope (SEM) produces a gray-scale image with depth and high clarity, which later is often colorized to illustrate different areas.

Funded by the following grant(s)

Science Education Partnership Award, NIH

Grant Number: 5R25RR018605