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Maintaining Muscle Mass in Space

Maintaining Muscle Mass in Space

Astronaut Sandra Magnus, Expedition 18, exercises on the advanced Resistive Exercise Device (aRED) aboard the ISS. Specialized exercise equipment that works in microgravity helps keep astronauts' muscles and bones from degenerating.
Courtesy of NASA.

Kenneth M. Baldwin, PhD, explains how and why muscles change during spaceflight, why this is important, and what can we do to limit muscle atrophy in space and on Earth.

Join Dr. Baldwin as he examines key properties of the skeletal muscle system and its inherent dependence on the force of gravity, and discusses what happens to muscles when gravity is eliminated, as during prolonged exposure to space flight or under conditions of prolonged bed rest (an analogue of spaceflight), and a strategy to maintain the integrity and functionality of skeletal muscle in the absence of gravity.

Companion slide set to the video, "Maintaining Muscle Mass in Space."

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Author(s): Kenneth M. Baldwin, PhD
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Slides: 1–12 of 19

Seeking Countermeasures to the Deleterious Effects of Space Travel on Skeletal Muscle


Motor Units and Musculoskeletal System

Motor Units and the Musculoskeletal System II

Myosin is the Muscle’s “Motor Protein”

Myosin, the “Motor” Molecule

The Pattern of Skeletal Myosin Heavy Chain (MHC) Isoform Transitions

Why Do Skeletal Muscle Fibers Atrophy During Space Flight?

Skeletal Muscle and Loading State

Absolute and Relative Muscle Weight in Response to Muscle Unloading in Rodents

Human Muscle Response Under Different Conditions of Unloading

Knee Extensor Muscle Size in Response to Different States of Unloading

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Funded by the following grant(s)

National Space Biomedical Research Institute

National Space Biomedical Research Institute

This work was supported by National Space Biomedical Research Institute through NASA cooperative agreement NCC 9-58.