Stress Drives Evolution in E. coli
Scanning electron micrograph of Escherichia coli, grown in culture and adhered to a cover slip.
Rocky Mountain Laboratories, NIAID, NIH
When starved, bacterial cells activate molecular mechanisms that promote mutations. A team led by Dr. Susan Rosenberg at BCM studied and described an elaborate gene network that increases the rate of mutations during the repair of double-stranded DNA in stressed E. coli cells. This work may lead to new drugs that thwart the emergence of antibiotic-resistant bacteria. Learn more here. BCM Article: Stress Drives Evolution in E. coli
Additional news stories on bacterial evolution and antibiotic resistance.