Molecular Genetics

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DNA and RNA structure and function, gene regulation, proteins, mutation, viral structures and replication, genomics, medical genetics
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A 3D Map of the Human Genome
Video
The human genome is two meters long but fits inside the microscopic nucleus of a cell. The genome also modulates the function of each cell, so that the cells operate differently. What makes this happen? Suhas Rao and Miriam Huntley of the Erez Aiden Lieberman Lab describe a 3D map of the human genome at kilobase resolution, revealing the principles of chromatin looping.
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How Does DNA Fold? The Loop Extrusion Model
Video
The human genome is two meters long, but it fits inside the microscopic nucleus of a cell. How is this possible? Research conducted in the Aiden Lab at Baylor College of Medicine suggests that the genome achieves this feat by forming loops and domains through a process called extrusion.
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Molecular Basis of Heredity: Part 1. Nucleic Acids
Presentation
Discover the fundamentals of DNA, RNA, nucleic acids and their roles within cells, with Raye Lynn Alford, PhD.
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Molecular Basis of Heredity: Part 2. Genomes
Presentation
Raye Lynn Alford, PhD, explains the structures and functions of genomes, and discusses how chromosomal changes lead to certain genetic disorders.
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Molecular Basis of Heredity: Part 3. Genetic Variation
Presentation
Join Raye Lynn Alford, PhD, as she explains the molecular basis of genetic variation, including mechanisms and types of DNA sequence variations, and patterns of inheritance of genetic disorders.
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Molecular Basis of Heredity: Part 4. Gene Identification and Tests
Presentation
Raye Lynn Alford, PhD, discusses processes of gene identification for purposes of disease research through specialized technologies and tests.
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The Pathway to Genomic Medicine
Presentation
Richard Gibbs, PhD, explains genomic medicine and its role in and relationship to genetic research, and outlines how technology and the study of genetics is transforming medicine.